Structure of PDB 4mqk Chain H

Receptor sequence
>4mqkH (length=145) Species: 9606 (Homo sapiens) [Search protein sequence]
HFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSA
SAIMGNPKVKAHGKKMLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDPE
NFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTGVASALSSRYH
3D structure
PDB4mqk Carbonmonoxy Structure of the Human Fetal Hemoglobin Mutant HbF Toms River alphawtgammaV67M
ChainH
Resolution2.242 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM H F41 F42 H63 M67 S70 L88 H92 K95 L96 N102 L106 L141 F40 F41 H62 M66 S69 L87 H91 K94 L95 N101 L105 L140
Gene Ontology
Molecular Function
GO:0004601 peroxidase activity
GO:0005344 oxygen carrier activity
GO:0005515 protein binding
GO:0019825 oxygen binding
GO:0020037 heme binding
GO:0031720 haptoglobin binding
GO:0031721 hemoglobin alpha binding
GO:0043177 organic acid binding
GO:0046872 metal ion binding
Biological Process
GO:0015670 carbon dioxide transport
GO:0015671 oxygen transport
GO:0042744 hydrogen peroxide catabolic process
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005829 cytosol
GO:0005833 hemoglobin complex
GO:0031838 haptoglobin-hemoglobin complex
GO:0072562 blood microparticle

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4mqk, PDBe:4mqk, PDBj:4mqk
PDBsum4mqk
PubMed
UniProtP69892|HBG2_HUMAN Hemoglobin subunit gamma-2 (Gene Name=HBG2)

[Back to BioLiP]