Structure of PDB 4lrh Chain H

Receptor sequence
>4lrhH (length=204) Species: 9606 (Homo sapiens) [Search protein sequence]
RTELLNVCMNAKHHKEKPGPEDKLHEQCRPWRKNACCSTNTSQEAHKDVS
YLYRFNWNHCGEMAPACKRHFIQDTCLYECSPNLGPWIQQVDQSWRKERV
LNVPLCKEDCEQWWEDCRTSYTCKSNWHKGWNWTSGFNKCAVGAACQPFH
FYFPTPTVLCNEIWTHSYKVSNYSRGSGRCIQMWFDPAQGNPNEEVARFY
AAAM
3D structure
PDB4lrh Structural basis for molecular recognition of folic acid by folate receptors.
ChainH
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FOL H Y60 D81 Y85 W102 W134 H135 K136 G137 W138 W140 W171 S174 Y53 D74 Y78 W95 W127 H128 K129 G130 W131 W133 W164 S167
External links
PDB RCSB:4lrh, PDBe:4lrh, PDBj:4lrh
PDBsum4lrh
PubMed23851396
UniProtP15328|FOLR1_HUMAN Folate receptor alpha (Gene Name=FOLR1)

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