Structure of PDB 4lar Chain H

Receptor sequence

>4larH (length=232) Species: 10090 (Mus musculus) [Search protein sequence]

EVQLQESGPSLVKPSQTLSLTCSVTGDSVTSGYWSWIRQFPGNKLDYMGY
ISYRGSTYYNPSLKSRISITRDTSKNQVYLQLKSVSSEDTATYYCSYFDS
DDYAMEYWGQGTSVTVSSGGGGSQIVLTQSPAIMSASPGEKVTLTCSASS
SVSSSHLYWYQQKPGSSPKLWIYSTSNLASGVPARFSGSGSGTSYSLTIS
SMEAEDAASYFCHQWSSFPFTFGSGTKLEIKR

3D structure

PDB

4lar Structural characterization of a therapeutic anti-methamphetamine antibody fragment: oligomerization and binding of active metabolites.

Chain

Resolution

2.38 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	1WE	H	Y33 F98 E106 H213 W215 F220	Y33 F98 E106 H213 W215 F220	PDBbind-CN: -logKd/Ki=4.68,Kd=20.7uM

External links

PDB	RCSB:4lar, PDBe:4lar, PDBj:4lar
PDBsum	4lar
PubMed	24349338

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