Structure of PDB 4kze Chain H

Receptor sequence

>4kzeH (length=225) Species: 10090 (Mus musculus) [Search protein sequence]

EVQLVESGGGLVQPGGSLRLSCAASGFYISYSSIHWVRQAPGKGLEWVAS
ISPYSGSTYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARQG
YRRRSGRGFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCL
VKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGT
QTYICNVNHKPSNTKVDKKVEPKSC

3D structure

PDB

4kze A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.

Chain

Resolution

2.404 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	H	Y34 P56 Y57 S58 S60 Y62 Q102 Y104 R105 R110	Y31 P53 Y54 S55 S57 Y59 Q99 Y101 R102 R107	PDBbind-CN: Kd=25nM

External links

PDB	RCSB:4kze, PDBe:4kze, PDBj:4kze
PDBsum	4kze
PubMed	24952597

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