Structure of PDB 4kgc Chain H

Receptor sequence
>4kgcH (length=95) Species: 8355 (Xenopus laevis) [Search protein sequence]
KTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRL
AHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
3D structure
PDB4kgc Ligand substitutions between ruthenium-cymene compounds can control protein versus DNA targeting and anticancer activity
ChainH
Resolution2.69 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna H R30 K31 S33 I36 Y37 R3 K4 S6 I9 Y10
BS02 dna H K28 T29 R30 Y39 I51 S52 S53 R83 S84 T85 K1 T2 R3 Y12 I24 S25 S26 R56 S57 T58
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4kgc, PDBe:4kgc, PDBj:4kgc
PDBsum4kgc
PubMed24637564
UniProtP02281|H2B11_XENLA Histone H2B 1.1

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