Structure of PDB 4j8x Chain H

Receptor sequence
>4j8xH (length=95) Species: 8355 (Xenopus laevis) [Search protein sequence]
KTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRL
AHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
3D structure
PDB4j8x Novel metal(II) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents
ChainH
Resolution2.87 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna H K31 S33 I36 Y37 K4 S6 I9 Y10
BS02 dna H K28 T29 S52 S53 R83 S84 T85 K1 T2 S25 S26 R56 S57 T58
BS03 RU7 H F67 E68 F40 E41
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4j8x, PDBe:4j8x, PDBj:4j8x
PDBsum4j8x
PubMed
UniProtP02281|H2B11_XENLA Histone H2B 1.1

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