Structure of PDB 4inh Chain H

Receptor sequence
>4inhH (length=168) Species: 524364 (Norovirus Hu/1968/US) [Search protein sequence]
DKAPPTLWSRVTKFGSGWGFWVSPTVFITTTHVVPTGVKEFFGEPLSSIA
IHQAGEFTQFRFSKKMRPDLTGMVLEEGCPEGTVCSVLIKRDSGELLPLA
VRMGAIASMRIQGRLVHGQSGMLLMDLGTIPGDCGAPYVHKRGNDWVVCG
VHAAATKSGNTVVCAVQA
3D structure
PDB4inh Structural basis of substrate specificity and protease inhibition in norwalk virus.
ChainH
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.66: calicivirin.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide H H30 I109 Q110 T134 P136 C139 A158 A159 A160 H32 I111 Q112 T129 P131 C134 A153 A154 A155
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:4inh, PDBe:4inh, PDBj:4inh
PDBsum4inh
PubMed23365454
UniProtQ83883|POLG_NVN68 Genome polyprotein (Gene Name=ORF1)

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