Structure of PDB 4hs8 Chain H

Receptor sequence

>4hs8H (length=225) Species: 9606 (Homo sapiens) [Search protein sequence]

EVQLVESGGGLVQPGGSLRLSCAASGYTFTNYWINWVRQAPGKGLEWVGD
IYPSDSFTNYNQNFKDRFTISRDKSKNTAYLQMNSLRAEDTAVYYCARSS
IYYGKDYVLDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCL
VKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGT
QTYICNVNHKPSNTKVDKKVEPKSC

3D structure

PDB

4hs8 Glycan shifting on hepatitis C virus (HCV) e2 glycoprotein is a mechanism for escape from broadly neutralizing antibodies.

Chain

Resolution

2.6 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	H	W33 Y52 F56 I97 Y98 Y100C	W33 Y52 F57 I101 Y102 Y107

External links

PDB	RCSB:4hs8, PDBe:4hs8, PDBj:4hs8
PDBsum	4hs8
PubMed	23458406

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