Structure of PDB 4gqp Chain H

Receptor sequence
>4gqpH (length=229) Species: 10090 (Mus musculus) [Search protein sequence]
EVQLQESGPSLVKPSQTLSLTCSVTGDSVTSGYWSWIRQFPGNKLDYMGY
ISYRGSTYYNPSLKSRISITRDTSKNQVYLQLKSVSSEDTATYYCTYFDS
DDYAMEYWGQGTSVTVSGGGSQIVLTQSPAIMSASPGEKVTLTCSASSSV
SSSHLYWYQQKPGSSPKLWIYSTSNLASGVPARFSGSGSGTSYSLTISSM
EAEDAASYFCHQWSSFPFTFGSGTKLEIK
3D structure
PDB4gqp Affinity improvement of a therapeutic antibody to methamphetamine and amphetamine through structure-based antibody engineering.
ChainH
Resolution2.0 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 B40 H Y33 S35 Y47 Y50 F95 E101 Y1034 Y1036 H1089 W1091 F1096 Y33 S35 Y47 Y50 F98 E106 Y156 Y158 H211 W213 F218 MOAD: Kd=0.79nM
PDBbind-CN: -logKd/Ki=9.60,Kd=0.25nM
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