Structure of PDB 4f1e Chain H

Receptor sequence
>4f1eH (length=66) Species: 9606 (Homo sapiens) [Search protein sequence]
AMINLHIQKDNPKIVHAFDMEDLGGKAVYCRCWRSKKFPFCDGAHTKHNE
ETGDNVGPLIIKKKET
3D structure
PDB4f1e Allosteric control in a metalloprotein dramatically alters function.
ChainH
Resolution2.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.6.1.3: cysteine transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FES H C72 R73 C74 C83 D84 G85 A86 H87 P100 C30 R31 C32 C41 D42 G43 A44 H45 P58
Gene Ontology
Molecular Function
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0010506 regulation of autophagy
Cellular Component
GO:0043231 intracellular membrane-bounded organelle

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4f1e, PDBe:4f1e, PDBj:4f1e
PDBsum4f1e
PubMed23271805
UniProtQ9NZ45|CISD1_HUMAN CDGSH iron-sulfur domain-containing protein 1 (Gene Name=CISD1)

[Back to BioLiP]