Structure of PDB 3oau Chain H

Receptor sequence

>3oauH (length=218) Species: 9606 (Homo sapiens) [Search protein sequence]

EVQLVESGGGLVKAGGSLRLSCGVSNFRISAHTMNWVRRVPGGGLEWVAS
ISTSSTYRDYADAVKGRFTVSRDDLEDFVYLQMHKMRVEDTAIYYCARKG
SDRLSDNDPFDAWGPGTVVTVSPASTKGPSVFPLAPSGTAALGCLVKDYF
PEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYIC
NVNHKPSNTKVDKKVEPK

3D structure

PDB

3oau Antibody 2G12 recognizes di-mannose equivalently in domain- and nondomain-exchanged forms but only binds the HIV-1 glycan shield if domain exchanged.

Chain

Resolution

1.9 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MAN	H	A31 S105 D106	A31 S105 D106
BS02	MAN	H	A31 H32 T33 K99 G100 S105 D106 N107 D108	A31 H32 T33 K99 G100 S105 D106 N107 D108

External links

PDB	RCSB:3oau, PDBe:3oau, PDBj:3oau
PDBsum	3oau
PubMed	20702629

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