Structure of PDB 3i3o Chain H

Receptor sequence

>3i3oH (length=270) Species: 261594 (Bacillus anthracis str. 'Ames Ancestor') [Search protein sequence]

HQNKQPGIESLMNPLPQFEDPNYKGSEKLKGKNVLITGGDSGIGRAVSIA
FAKEGANIAIAYLDEEGDANETKQYVEKEGVKCVLLPGDLSDEQHCKDIV
QETVRQLGSLNILVNNVAQQYPQQGLEYITAEQLEKTFRINIFSYFHVTK
AALSHLKQGDVIINTASIVAYEGNETLIDYSATKGAIVAFTRSLSQSLVQ
KGIRVNGVAPGPIWTPLIPSSFSQFGSNVPMQRPGQPYELAPAYVYLASS
DSSYVTGQMIHVNGGVIVNG

3D structure

PDB

3i3o 2.06 Angstrom resolution crystal structure of a short chain dehydrogenase from Bacillus anthracis str. 'Ames Ancestor' in complex with NAD-acetone

Chain

Resolution

2.06 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	G55 S180 L190 Y193 K197
Catalytic site (residue number reindexed from 1)	G42 S167 L177 Y180 K184
Enzyme Commision number	?

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MG	H	D53 S54 E78	D40 S41 E65
BS02	NAE	H	D53 S54 G55 I56 Y75 L76 E78 G101 D102 L103 N129 V130 A131 Q132 Q133 T178 S180 Y193 K197 P223 G224 P225 I226 T228 P229 L230	D40 S41 G42 I43 Y62 L63 E65 G88 D89 L90 N116 V117 A118 Q119 Q120 T165 S167 Y180 K184 P210 G211 P212 I213 T215 P216 L217

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0016491	oxidoreductase activity
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
GO:0046872	metal ion binding

View graph for
Molecular Function

External links

PDB	RCSB:3i3o, PDBe:3i3o, PDBj:3i3o
PDBsum	3i3o
PubMed
UniProt	A0A6L8PL20

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