Structure of PDB 3bsu Chain H

Receptor sequence
>3bsuH (length=47) Species: 9606 (Homo sapiens) [Search protein sequence]
HMFYAVRRGRKTGVFLTWNECRAQVDRFPAARFKKFATEDEAWAFVR
3D structure
PDB3bsu Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD.
ChainH
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.26.4: ribonuclease H.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna H R52 F53 A55 R27 F28 A30 PDBbind-CN: Kd=0.2uM
BS02 dna H W43 F58 K60 W18 F33 K35 PDBbind-CN: Kd=0.2uM
External links
PDB RCSB:3bsu, PDBe:3bsu, PDBj:3bsu
PDBsum3bsu
PubMed18337749
UniProtO60930|RNH1_HUMAN Ribonuclease H1 (Gene Name=RNASEH1)

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