Structure of PDB 3bsu Chain H
Receptor sequence
>3bsuH (length=47) Species:
9606
(Homo sapiens) [
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HMFYAVRRGRKTGVFLTWNECRAQVDRFPAARFKKFATEDEAWAFVR
3D structure
PDB
3bsu
Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD.
Chain
H
Resolution
2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
3.1.26.4
: ribonuclease H.
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
rna
H
R52 F53 A55
R27 F28 A30
PDBbind-CN
: Kd=0.2uM
BS02
dna
H
W43 F58 K60
W18 F33 K35
PDBbind-CN
: Kd=0.2uM
External links
PDB
RCSB:3bsu
,
PDBe:3bsu
,
PDBj:3bsu
PDBsum
3bsu
PubMed
18337749
UniProt
O60930
|RNH1_HUMAN Ribonuclease H1 (Gene Name=RNASEH1)
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