Structure of PDB 2yk1 Chain H

Receptor sequence
>2yk1H (length=182) Species: 9606 (Homo sapiens) [Search protein sequence]
QLLESGPGLVKPSETLSLTCTVSGGSIWGWIRQPPGKGLEWIGSIYSSGS
TYYNPSLKSRVTTSVDTSKNQFSLRLSSVTAADTAVYYCVAWFGDLLSLK
GVELWGQGTLVTVSSASTKGPSVFPLALGCLVKDYFPEPVTVSWNLTSGV
HTFPAVLQSSGLYSLSSVVTCNVDHKPSNTKV
3D structure
PDB2yk1 Different Binding Modes of Free and Carrier-Protein-Coupled Nicotine in a Human Monoclonal Antibody.
ChainH
Resolution1.85 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NCT H I29 G31 S50 V93 E101 I27 G29 S44 V90 E103 MOAD: Kd=7.4nM
PDBbind-CN: -logKd/Ki=8.13,Kd=7.4nM
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