Structure of PDB 2vvl Chain H

Receptor sequence
>2vvlH (length=478) Species: 5061 (Aspergillus niger) [Search protein sequence]
MTSRDGYQWTPETGLTQGVPSLGVISPPTNIPWDVIVIGGGYCGLTATRD
LTVAGFKTLLLEARDRIGGRSWSSNIDGYPYEMGGTWVHWHQSHVWREIT
RYKMHNALSPSFNFSRGVNHFQLRTNPTTSTYMTHEAEDELLRSALHKFT
NVDGTNGRTVLPFPHDMFYVPEFRKYDEMSYSERIDQIRDELSLNERSSL
EAFILLCSGGTLENSSFGEFLHWWAMSGYTYQGCMDCLMSYKFKDGQSAF
ARRFWEEAAGTGRLGYVFGCPVRSVVNERDAARVTARDGREFVAKRVVCT
IPLNVLSTIQFSPALSTERISAMQAGHVSMCTKVHAEVDNKDMRSWTGIA
YPFNKLCYAIGDGTTPAGNTHLVCFGTDANHIQPDEDVRETLKAVGQLAP
GTFGVKRLVFHNWVKDEFAKGAWFFSRPGMVSECLQGLREKHGGVVFANS
DWALGWRSFIDGAIEEGTRAARVVLEEL
3D structure
PDB2vvl The Structure of Monoamine Oxidase from Aspergillus Niger Provides a Molecular Context for Improvements in Activity Obtained by Directed Evolution.
ChainH
Resolution2.45 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H96
Catalytic site (residue number reindexed from 1) H89
Enzyme Commision number 1.4.3.4: monoamine oxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD H G48 C50 E69 A70 R71 G76 R77 G91 G92 T93 W94 P278 V279 I308 W420 F425 A429 W430 N456 S457 S465 F466 I467 A470 G41 C43 E62 A63 R64 G69 R70 G84 G85 T86 W87 P271 V272 I301 W413 F418 A422 W423 N449 S450 S458 F459 I460 A463
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0097621 monoamine oxidase activity
Cellular Component
GO:0005777 peroxisome

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Molecular Function
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Cellular Component
External links
PDB RCSB:2vvl, PDBe:2vvl, PDBj:2vvl
PDBsum2vvl
PubMed18951902
UniProtP46882|AOFN_ASPNG Monoamine oxidase N (Gene Name=maoN)

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