Structure of PDB 2qsc Chain H

Receptor sequence

>2qscH (length=211) Species: 9606 (Homo sapiens) [Search protein sequence]

QVQLVQSGGGLVQPGGSLRLSCAAFGFNFSSYVMHWVRQAPGQGLEYLSA
ISSDGETTYHANSVKGRFTSSRDNSKNTLFLQMGSLRTEDVAVYYCARDR
YYETSGSNAFDVWGQGTMVVVSSASTKGPSVFPLAPCTAALGCLVKDYFP
EPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSTQTYTCNVDHK
PSNTKVDKTVE

3D structure

PDB

2qsc Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization.

Chain

Resolution

2.8 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	H	S52 Y58 Y97 N100D	S52 Y59 Y101 N108
BS02	ZN	H	D53 E55	D54 E56

External links

PDB	RCSB:2qsc, PDBe:2qsc, PDBj:2qsc
PDBsum	2qsc
PubMed	18068724

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