Structure of PDB 2puq Chain H

Receptor sequence
>2puqH (length=254) Species: 9606 (Homo sapiens) [Search protein sequence]
IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWR
NLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPV
VLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNV
PRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHY
RGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLR
APFP
3D structure
PDB2puq Engineering the substrate and inhibitor specificities of human coagulation Factor VIIa
ChainH
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.21: coagulation factor VIIa.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide H H193 P321 D338 S339 C340 S344 S363 W364 G365 G367 H41 P169 D186 S187 C188 S192 S211 W212 G213 G215
BS02 BGC H H193 S344 H41 S192
BS03 CA H E210 D212 E215 H216 E220 E58 D60 E63 H64 E68
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2puq, PDBe:2puq, PDBj:2puq
PDBsum2puq
PubMed17456045
UniProtP08709|FA7_HUMAN Coagulation factor VII (Gene Name=F7)

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