Structure of PDB 2on5 Chain H

Receptor sequence
>2on5H (length=206) Species: 51031 (Necator americanus) [Search protein sequence]
MVHYKLTYFAGRGLAEPIRQIFALAGQKYEDVRYTFQEWPKHKDEMPFGQ
IPVLEEDGKQLAQSFAIARYLSRKFGFAGKTPFEEALVDSVADQYKDYIN
EIRPYLRVVAGVDQGDPEKLFKELLLPAREKFFGFMKKFLEKSKSGYLVG
DSVTYADLCLAEHTSGIAAKFPSIYDGFPEIKAHAEKVRSIPALKKWIET
RPETKF
3D structure
PDB2on5 X-ray structures of Na-GST-1 and Na-GST-2 two glutathione s-transferase from the human hookworm Necator americanus
ChainH
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y8 L14 R19 V109
Catalytic site (residue number reindexed from 1) Y8 L14 R19 V109
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH H Y8 F9 L14 W39 Q50 I51 Q63 S64 Y8 F9 L14 W39 Q50 I51 Q63 S64
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0016740 transferase activity
Biological Process
GO:0006749 glutathione metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2on5, PDBe:2on5, PDBj:2on5
PDBsum2on5
PubMed17594497
UniProtD3U1A6

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