Structure of PDB 2hrp Chain H

Receptor sequence

>2hrpH (length=226) Species: 10090 (Mus musculus) [Search protein sequence]

DVQLVESGGGLVQPGGSRKLSCAASGFTFMRFGMHWVRQAPEKGLEWVAY
ISSGSSTIYYADTVKGRFTISRDNPKNTLFLQMTSLRSEDTALYYCARSG
GIERYDGTYYVMDYWGQGTSVTVSSAKTTPPSVYPLAPGSAAQTNSMVTL
GCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSPR
PSETVTCNVAHPASSTKVDKKIVPRD

3D structure

PDB

2hrp Three-dimensional structure of an Fab-peptide complex: structural basis of HIV-1 protease inhibition by a monoclonal antibody.

Chain

Resolution

2.2 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	H	Y50 Y58 R100 D100B G100C T100D Y100E Y100F	Y50 Y59 R104 D106 G107 T108 Y109 Y110

External links

PDB	RCSB:2hrp, PDBe:2hrp, PDBj:2hrp
PDBsum	2hrp
PubMed	9150407

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