Structure of PDB 2gxa Chain H

Receptor sequence
>2gxaH (length=274) [Search protein sequence]
GSLQTEKFDFGTMVQWAYDHKYAEESKIAYEYALAAGSDSNARAFLATNS
QAKHVKDCATMVRHYLRAETQALSMPAYIKARCKLATGEGSWKSILTFFN
YQNIELITFINALKLWLKGIPKKNCLAFIGPPNTGKSMLCNSLIHFLGGS
VLSFANHKSHFWLASLADTRAALVDDATHACWRYFDTYLRNALDGYPVSI
DRKHKAAVQIKAPPLLVTSNIDVQAEDRYLYLHSRVQTFRFEQPCTDESG
EQPFNITDADWKSFFVRLWGRLDL
3D structure
PDB2gxa Mechanism of DNA translocation in a replicative hexameric helicase.
ChainH
Resolution3.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna H F464 K506 H507 F161 K203 H204
BS02 ADP H K425 Y499 K122 Y196
BS03 MG H S440 D479 S137 D176
BS04 ADP H N436 T437 G438 K439 S440 N558 N133 T134 G135 K136 S137 N255
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0005524 ATP binding
Biological Process
GO:0006260 DNA replication

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2gxa, PDBe:2gxa, PDBj:2gxa
PDBsum2gxa
PubMed16855583
UniProtP03116|VE1_BPV1 Replication protein E1 (Gene Name=E1)

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