Structure of PDB 2fx7 Chain H

Receptor sequence

>2fx7H (length=228) Species: 9606 (Homo sapiens) [Search protein sequence]

QVQLVQSGAEVKRPGSSVTVSCKASGGSFSTYALSWVRQAPGRGLEWMGG
VIPLLTITNYAPRFQGRITITADRSTSTAYLELNSLRPEDTAVYYCAREG
TTGWGWLGKPIGAFAHWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTA
ALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPS
SSLGTQTYICNVNHKPSNTKVDKKVEPK

3D structure

PDB

2fx7 Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.

Chain

Resolution

1.76 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	H	T31 A33 G50 V51 I52 I56 N58 E95 G100D K100E P100F	T31 A33 G50 V51 I52 I57 N59 E99 G108 K109 P110

External links

PDB	RCSB:2fx7, PDBe:2fx7, PDBj:2fx7
PDBsum	2fx7
PubMed	17125793

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