Structure of PDB 2fr4 Chain H

Receptor sequence

>2fr4H (length=214) Species: 10090 (Mus musculus) [Search protein sequence]

QVKLLESGPELVKPGASVKMSCKASGYTFTSYVMHWVKQKPGQGLEWIGY
INPYNDGTKYNEKFKGKATLTSDKSSSTAYMELSSLTSEDSAVYYCVRGG
YRPYYAMDYWGQGTSVTVSSAKTTPPSVYPLAPNSMVTLGCLVKGYFPEP
VTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAH
PASSTKVDKKIVPR

3D structure

PDB

2fr4 Impact of DNA hairpin folding energetics on antibody-ssDNA association.

Chain

Resolution

1.95 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	H	T30 S31 Y53 Y97 R98	T30 S31 Y54 Y101 R102	PDBbind-CN: Kd=4uM
BS02	dna	H	Y97 R98 Y100 Y100A A100B	Y101 R102 Y104 Y105 A106	PDBbind-CN: Kd=4uM

External links

PDB	RCSB:2fr4, PDBe:2fr4, PDBj:2fr4
PDBsum	2fr4
PubMed	18028946

[Back to BioLiP]