Structure of PDB 2e27 Chain H

Receptor sequence

>2e27H (length=116) Species: 10090 (Mus musculus) [Search protein sequence]

QVQLLESGAELARPGASVKLSCKASGYTFTTYWMQWVRQRPGQGLEWIGA
IYPGNGDTRYSQKFKGKATLTADTSSSTASMQLSSLASEDSAVYYCARSD
YGGDYWGQGTSVTVSS

3D structure

PDB

2e27 Critical contribution of aromatic rings to specific recognition of polyether rings. The case of ciguatoxin CTX3C-ABC and its specific antibody 1C49.

Chain

Resolution

1.7 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	AB0	H	W33 Q35 A50 S99 D100 Y1001	W33 Q35 A50 S99 D100 Y101	MOAD: Ka=2220000000M^-1 PDBbind-CN: -logKd/Ki=9.35,Kd=0.45nM

External links

PDB	RCSB:2e27, PDBe:2e27, PDBj:2e27
PDBsum	2e27
PubMed	18326040

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