Structure of PDB 2clv Chain H

Receptor sequence

>2clvH (length=278) Species: 10090 (Mus musculus) [Search protein sequence]

GPHSLRYFVTAVSRPGLGEPRFISVGYVDNTEFVRFDSDAENPRYEPRAR
WMEQEGPEYWERETQKAKGNEQSFRVDLRTLLGYYNQSKGGSHTIQVISG
CEVGSDGRLLRGYQQYAYDGCDYIALNEDLKTWTAADMAALITKHKWEQA
GEAERLRAYLEGTCVEWLRRYLKNGNATLLRTDSPKAHVTHHSRPEDKVT
LRCWALGFYPADITLTWQLNGEELIQDMELVETRPAGDGTFQKWASVVVP
LGKEQYYTCHVYHQGLPEPLTLRWEPPP

3D structure

PDB

2clv Distinct orientation of the alloreactive monoclonal CD8 T cell activation program by three different peptide/MHC complexes.

Chain

Resolution

1.9 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	H	Y7 Y45 E63 K66 A67 G69 N70 D77 Y84 S99 Y116 T143 K146 W147 E152 R155 L156 Y159 W167 Y171 P278	Y7 Y45 E63 K66 A67 G69 N70 D77 Y84 S99 Y116 T143 K146 W147 E152 R155 L156 Y159 W167 Y171 P278

External links

PDB	RCSB:2clv, PDBe:2clv, PDBj:2clv
PDBsum	2clv
PubMed	16761314
UniProt	P01901\|HA1B_MOUSE H-2 class I histocompatibility antigen, K-B alpha chain (Gene Name=H2-K1)

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