Structure of PDB 2cgr Chain H

Receptor sequence
>2cgrH (length=214) Species: 10090 (Mus musculus) [Search protein sequence]
RVQLLESGAELMKPGASVQISCKATGYTFSEYWIEWVKERPGHGLEWIGE
ILPGSGRTNYREKFKGKATFTADTSSNTAYMQLSSLTSEDSAVYYCTRGY
SSMDYWGQGTSVTVSAAKTTPPSVYPLAPGCGDTTGSSVTLGCLVKGYFP
ESVTVTWNSGSLSSSVHTFPALLQSGLYTMSSSVTVPSSTWPSQTVTCSV
AHPASSTTVDKKLE
3D structure
PDB2cgr Local and transmitted conformational changes on complexation of an anti-sweetener Fab.
ChainH
Resolution2.2 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GAS H W33 E35 E50 R57 N59 Y100 S101 S102 W33 E35 E50 R57 N59 Y100 S101 S102 MOAD: Kd=53nM
PDBbind-CN: -logKd/Ki=7.28,Kd=53nM
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