Structure of PDB 2b1a Chain H

Receptor sequence

>2b1aH (length=226) Species: 9606 (Homo sapiens) [Search protein sequence]

EIQLEQSGAEVKKSGESLKISCQTSGYSFSDYWIGWVRQMPGKGLEWMGI
FYPGDSDSRYSPSFEGQVTMSADRSTNTAHLQWSSLKPSDTALYYCARLG
GDYEDSGADAFDFWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALG
CLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSL
GTQTYICNVNHKPSNTKVDKKVEPKS

3D structure

PDB

2b1a Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity.

Chain

Resolution

2.348 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	H	D31 Y32 W33 Y52 D54 D56 L95 D98 E100 D100A S100B G100C A100D	D31 Y32 W33 Y52 D55 D57 L99 D102 E104 D105 S106 G107 A108

External links

PDB	RCSB:2b1a, PDBe:2b1a, PDBj:2b1a
PDBsum	2b1a
PubMed	16731948

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