Structure of PDB 1zhs Chain H

Receptor sequence

>1zhsH (length=113) Species: 44822 (Microcystis viridis)

ASYKVNIPAGPLWSNAEAQQVGPKIAAAHQGNFTGQWTTVVESAMSVVEV
ELQVENTGIHEFKTDVLAGPLWSNDEAQKLGPQIAASYGAEFTGQWRTIV
EGVMSVIQIKYTF

3D structure

• PDB: 1zhs Crystal Structures of the HIV-1 Inhibitory Cyanobacterial Protein MVL Free and Bound to Man3GlcNAc2: STRUCTURAL BASIS FOR SPECIFICITY AND HIGH-AFFINITY BINDING TO THE CORE PENTASACCHARIDE FROM N-LINKED OLIGOMANNOSIDE.
• Chain: H
• Resolution: 1.8 Å

Enzymatic activity

• Enzyme Commision number: 3.2.1.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	BMA	H	Q36 W37	Q36 W37
BS02	MAN	H	G35 Q36	G35 Q36
BS03	BMA	H	Q95 W96	Q95 W96
BS04	MAN	H	G94 Q95	G94 Q95

Gene Ontology

Molecular Function

• GO:0016798 hydrolase activity, acting on glycosyl bonds
• GO:0030246 carbohydrate binding

Biological Process

• GO:0050688 regulation of defense response to virus

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:1zhs, PDBe:1zhs, PDBj:1zhs
• PDBsum: 1zhs
• PubMed: 15937331
• UniProt: Q9RHG4|MVL_MICVR Lectin MVL (Gene Name=mvl)