Structure of PDB 1vpo Chain H

Receptor sequence

>1vpoH (length=221) Species: 10090 (Mus musculus) [Search protein sequence]

EVKLVESGGGLVKPGGSLKLSCAASGFTFSRYALSWVRQTADKRLEWVAS
IVSGGNTYYSGSVKGRFTISRDIARNILYLQMSSLRSEDTAMYYCARAYY
GYVGLVHWGQGTLVTVSSAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGY
FPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTC
NVAHPASSTKVDKKIVPRDCG

3D structure

PDB

1vpo Crystal Structure of an in Vitro Affinity- and Specificity-matured Anti-testosterone Fab in Complex with Testosterone. IMPROVED AFFINITY RESULTS FROM SMALL STRUCTURAL CHANGES WITHIN THE VARIABLE DOMAINS

Chain

Resolution

2.15 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	TES	H	S50 Y58 A98 Y102 G104 L105	S50 Y58 A98 Y102 G104 L105	MOAD: Kd=0.000000064M

External links

PDB	RCSB:1vpo, PDBe:1vpo, PDBj:1vpo
PDBsum	1vpo
PubMed	12196551

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