Structure of PDB 1u3h Chain H

Receptor sequence
>1u3hH (length=189) Species: 10090 (Mus musculus) [Search protein sequence]
GDSERHFVVQFQPFCYFTNGTQRIRYVTRYIYNREEYLRFDSDVGEYRAV
TELGRPDAEYYNKQYLERTRAELDTVCRYNYEETEVPTSLRRLEQPNVVI
SLSRTEALNHHNTLVCSVTDFYPAKIKVRWFRNGQEETVGVSSTQLIRNG
DWTFQVLVMLEMTPRRGEVYTCHVEHPSLKSPITVEWRA
3D structure
PDB1u3h Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: insights into MHC bias and antigen specificity
ChainH
Resolution2.42 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide H F11 P13 Y26 Y30 D57 Y61 Y67 E74 Y81 N82 F11 P13 Y26 Y30 D57 Y61 Y65 E72 Y79 N80
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:1u3h, PDBe:1u3h, PDBj:1u3h
PDBsum1u3h
PubMed15664161
UniProtP06344|HB2U_MOUSE H-2 class II histocompatibility antigen, A-U beta chain

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