Structure of PDB 1rfu Chain H

Receptor sequence
>1rfuH (length=312) Species: 9940 (Ovis aries) [Search protein sequence]
MEEECRVLSIQSHVVRGYVGNRAATFPLQVLGFEVDAVNSVQFSNHTGYS
HWKGQVLNSDELQELYDGLKLNHVNQYDYVLTGYTRDKSFLAMVVDIVQE
LKQQNPRLVYVCDPVMGDQRNGEGAMYVPDDLLPVYREKVVPVADIITPN
QFEAELLTGRKIHSQEEALEVMDMLHSMGPDTVVITSSNLLSPRGSDYLM
ALGSQRTRAPDGSVVTQRIRMEMHKVDAVFVGTGDLFAAMLLAWTHKHPN
NLKVACEKTVSAMHHVLQRTIKCAKAKSGEGVKPSPAQLELRMVQSKKDI
ESPEIVVQATVL
3D structure
PDB1rfu Conformational changes in the reaction of pyridoxal kinase
ChainH
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.35: pyridoxal kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP H S12 V19 T47 Y84 Y127 V231 G232 G234 D235 S12 V19 T47 Y84 Y127 V231 G232 G234 D235
BS02 ADP H T186 S187 L199 M223 K225 V226 T233 G234 M263 L267 T186 S187 L199 M223 K225 V226 T233 G234 M263 L267
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008478 pyridoxal kinase activity
GO:0016301 kinase activity
GO:0046872 metal ion binding
Biological Process
GO:0009443 pyridoxal 5'-phosphate salvage
GO:0016310 phosphorylation
GO:0042816 vitamin B6 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1rfu, PDBe:1rfu, PDBj:1rfu
PDBsum1rfu
PubMed14722069
UniProtP82197|PDXK_SHEEP Pyridoxal kinase (Gene Name=PDXK)

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