Structure of PDB 1qfk Chain H

Receptor sequence
>1qfkH (length=252) Species: 9606 (Homo sapiens) [Search protein sequence]
IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWR
NLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPV
VLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNV
PRLMTQDCLQQSVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRG
TWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAP
FP
3D structure
PDB1qfk Structure of human factor VIIa and its implications for the triggering of blood coagulation.
ChainH
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.21: coagulation factor VIIa.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0Z6 H H193 T238 T239 P321 D338 S339 C340 K341 G342 S344 S363 W364 G365 Q366 H41 T86 T87 P167 D184 S185 C186 K187 G188 S190 S209 W210 G211 Q212
BS02 CA H E210 D212 E215 E220 E58 D60 E63 E68
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1qfk, PDBe:1qfk, PDBj:1qfk
PDBsum1qfk
PubMed10430872
UniProtP08709|FA7_HUMAN Coagulation factor VII (Gene Name=F7)

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