Structure of PDB 1pzu Chain H

Receptor sequence
>1pzuH (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
WPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGY
MENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKV
LEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRV
HIPESSGRIVSLQTASNPIECSQELPMVERQDTDSCLVYGGQQMILTGQN
FTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRT
PVKVNFYVINGKRKRSQPQHFTYHPV
3D structure
PDB1pzu An asymmetric NFAT1 dimer on a pseudo-palindromic KB-like DNA site
ChainH
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna H Y424 T426 K520 R522 N523 R537 K538 Y26 T28 K122 R124 N125 R139 K140
BS02 dna H R421 S429 R430 Q571 R23 S31 R32 Q173
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1pzu, PDBe:1pzu, PDBj:1pzu
PDBsum1pzu
PubMed12949491
UniProtQ13469|NFAC2_HUMAN Nuclear factor of activated T-cells, cytoplasmic 2 (Gene Name=NFATC2)

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