Structure of PDB 1pk8 Chain H

Receptor sequence
>1pk8H (length=286) Species: 10116 (Rattus norvegicus) [Search protein sequence]
AARVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGF
SVDMEVRSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSV
YNFCDKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVK
MGHAHSGMGKVKVDNQHDFQDIASVVALTKTYATAEPFIDAKYDVRVQKI
GQNYKAYMRTWKLEQIAMSDRYKLWVDTCSEIFGGLDICAVEALHGKDGR
DHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMTQA
3D structure
PDB1pk8 Tetramerization and ATP binding by a protein comprising the A, B, and C domains of rat synapsin I.
ChainH
Resolution2.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA H E373 E386 E242 E255
BS02 ATP H V267 K269 H274 S275 G276 K279 E305 F307 I308 R328 W335 L375 E386 V148 K150 H155 S156 G157 K160 E186 F188 I189 R209 W211 L244 E255 MOAD: Kd=120nM
Gene Ontology
Biological Process
GO:0007269 neurotransmitter secretion
Cellular Component
GO:0008021 synaptic vesicle

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1pk8, PDBe:1pk8, PDBj:1pk8
PDBsum1pk8
PubMed14688264
UniProtP09951|SYN1_RAT Synapsin-1 (Gene Name=Syn1)

[Back to BioLiP]