Structure of PDB 1ofr Chain H

Receptor sequence
>1ofrH (length=346) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
EEDVRILGYDPLASPALLQVQIPATPTSLETAKRGRREAIDIITGKDDRV
LVIVGPCSIHDLEAAQEYALRLKKLSDELKGDLSIIMRAYLEKPRTTVGW
KGLINDPDVNNTFNINKGLQSARQLFVNLTNIGLPIGSEMLDTISPQYLA
DLVSFGAIGARTTESQLHRELASGLSFPVGFKNGTDGTLNVAVDACQAAA
HSHHFMGVTKHGVAAITTTKGNEHCFVILRGGKKGTNYDAKSVAEAKAQL
PAGSNGLMIDYSHGNSNKDFRNQPKVNDVVCEQIANGENAITGVMIESNI
NEGNQGIPAAGLKYGVSITDACIGWETTEDVLRKLAAAVRQRREVN
3D structure
PDB1ofr Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism.
ChainH
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.54: 3-deoxy-7-phosphoheptulonate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN H C76 H282 E316 D342 C57 H263 E297 D320
BS02 PHE H T162 P165 Q166 A169 L190 L194 S195 T143 P146 Q147 A150 L171 L175 S176
BS03 PHE H E21 D22 E2 D3
Gene Ontology
Molecular Function
GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity
GO:0016740 transferase activity
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009058 biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009423 chorismate biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:1ofr, PDBe:1ofr, PDBj:1ofr
PDBsum1ofr
PubMed15019786
UniProtP32449|AROG_YEAST Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited (Gene Name=ARO4)

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