Structure of PDB 1lwu Chain H

Receptor sequence
>1lwuH (length=315) Species: 7757 (Petromyzon marinus) [Search protein sequence]
AQKEIENRYKEVKIRIESTVAGSLRSMKSVLEHLRAKMQRMEEAIKTQKE
LCSAPCTVNCRVPVVSGMHCEDIYRNGGRTSEAYYIQPDLFSEPYKVFCD
MESHGGGWTVVQNRVDGSSNFARDWNTYKAEFGNIAFGNGKSICNIPGEY
WLGTKTVHQLTKQHTQQVLFDMSDWEGSSVYAQYASFRPENEAQGYRLWV
EDYSGNAGNALLEGATQLMGDNRTMTIHNGMQFSTFDRDNDNWNPGDPTK
HCSREDAGGWWYNRCHAANPNGRYYWGGIYTKEQADYGTDDGVVWMNWKG
SWYSMRQMAMKLRPK
3D structure
PDB1lwu Crystal structure of fragment D from lamprey fibrinogen complexed with the peptide Gly-His-Arg-Pro-amide.
ChainH
Resolution2.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide H N384 M387 W405 E417 D418 R426 C427 H428 T451 D452 M458 N222 M225 W243 E255 D256 R264 C265 H266 T289 D290 M296
BS02 CA H D401 D403 W405 K412 D239 D241 W243 K250
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1lwu, PDBe:1lwu, PDBj:1lwu
PDBsum1lwu
PubMed12162736
UniProtP02678|FIBB_PETMA Fibrinogen beta chain (Fragments)

[Back to BioLiP]