Structure of PDB 1k22 Chain H

Receptor sequence
>1k22H (length=251) Species: 9606 (Homo sapiens) [Search protein sequence]
IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPW
DKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDI
ALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETGQP
SVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGG
PFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF
G
3D structure
PDB1k22 Factorising ligand affinity: a combined thermodynamic and crystallographic study of trypsin and thrombin inhibition.
ChainH
Resolution1.93 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.5: thrombin.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0005509 calcium ion binding
Biological Process
GO:0006508 proteolysis
GO:0007596 blood coagulation

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Molecular Function

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Biological Process
External links
PDB RCSB:1k22, PDBe:1k22, PDBj:1k22
PDBsum1k22
PubMed11676542
UniProtP00734|THRB_HUMAN Prothrombin (Gene Name=F2)

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