Structure of PDB 1jym Chain H

Receptor sequence
>1jymH (length=173) Species: 5833 (Plasmodium falciparum) [Search protein sequence]
EIKIVKYPDPILRRRSEVTNFDDNLKRVVRKMFDIMYESKGIGLSAPQVN
ISKRIIVWNALYEKRKEENERIFINPSIVEQSLVKLKLIEGCLSFGIEGK
VERPSIVSISYYDINGYKHLKILKGIHSRIFQHEFDHLNGTLFIDKMTQV
DKKKVRPKLNELIRDYKATHSEE
3D structure
PDB1jym Crystals of peptide deformylase from Plasmodium falciparum reveal critical characteristics of the active site for drug design.
ChainH
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G106 Q111 C155 L156 H196 E197 H200
Catalytic site (residue number reindexed from 1) G43 Q48 C92 L93 H133 E134 H137
Enzyme Commision number 3.5.1.88: peptide deformylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CO H Q111 C155 H196 H200 Q48 C92 H133 H137
Gene Ontology
Molecular Function
GO:0042586 peptide deformylase activity

View graph for
Molecular Function
External links
PDB RCSB:1jym, PDBe:1jym, PDBj:1jym
PDBsum1jym
PubMed12005434
UniProtQ8I372

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