Structure of PDB 1hwt Chain H

Receptor sequence
>1hwtH (length=73) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
KRNRIPLSCTICRKRKVKCDKLRPHCQQCTKTGVAHLCHYMEQTWAEEAE
KELLKDNELKKLRERVKSLEKTL
3D structure
PDB1hwt Structure of a HAP1-DNA complex reveals dramatically asymmetric DNA binding by a homodimeric protein.
ChainH
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna H K106 K110 K51 K55
BS02 dna H R57 N58 R59 K71 W100 R2 N3 R4 K16 W45
BS03 dna H K56 R57 R59 P61 S63 R68 K71 K73 C74 K1 R2 R4 P6 S8 R13 K16 K18 C19
BS04 ZN H H80 H91 H25 H36
BS05 ZN H C64 C67 C74 C81 C9 C12 C19 C26
BS06 ZN H C64 C81 C84 C93 C9 C26 C29 C38
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1hwt, PDBe:1hwt, PDBj:1hwt
PDBsum1hwt
PubMed9886294
UniProtP0CS82|HAP1_YEASX Heme-responsive zinc finger transcription factor HAP1 (Gene Name=HAP1)

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