Structure of PDB 1gaf Chain H

Receptor sequence
>1gafH (length=217) Species: 9606 (Homo sapiens) [Search protein sequence]
QVQLQQSGAELVKPGASVKLSCTASGFNIKDTYMHWVKQRPKQGLEWIGR
IDPANVDTKYDPKFQDKATITADTSSKTTYLQLSSLTSEDTAVYYCASYY
GIYWGQGTTLTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEP
VTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVN
HKPSNTKVDKKVEPKSC
3D structure
PDB1gaf The immunological evolution of catalysis.
ChainH
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NPE H Y33 H35 Y100 G101 Y33 H35 Y100 G101 MOAD: Kd=10nM
PDBbind-CN: -logKd/Ki=8.00,Kd=10nM
External links
PDB RCSB:1gaf, PDBe:1gaf, PDBj:1gaf
PDBsum1gaf
PubMed8599084
UniProtP01857|IGHG1_HUMAN Immunoglobulin heavy constant gamma 1 (Gene Name=IGHG1)

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