Structure of PDB 1etz Chain H

Receptor sequence
>1etzH (length=228) Species: 10090 (Mus musculus) [Search protein sequence]
QVTLKESGPGILQPSQTLSLTCSFSGFSLSTSGMGVGWIRQPSGEGLEWL
ADIWWNDKKYYNPSLKSRLTVSKDTSSNQVFLKITSVDTSDTATYHCARR
TFSYYYGSSFYYFDNWGQGTTLTVSSAKTTPPSVYPLAPGCGDTTGSSVT
LGCLVKGYFPESVTVTWNSGSLSSSVHTFPALLQSGLYTMSSSVTVPSST
WPSQTVTCSVAHPASSTTVDKKLEPSGP
3D structure
PDB1etz The three-dimensional structure of a complex of a murine Fab (NC10. 14) with a potent sweetener (NC174): an illustration of structural diversity in antigen recognition by immunoglobulins.
ChainH
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GAS H K58 Y60 R100 F102 Y104 Y111 K58 Y60 R100 F102 Y104 Y111 PDBbind-CN: -logKd/Ki=7.24,Kd=58nM
External links
PDB RCSB:1etz, PDBe:1etz, PDBj:1etz
PDBsum1etz
PubMed10993728
UniProtP01867|IGG2B_MOUSE Immunoglobulin heavy constant gamma 2B (Gene Name=Ighg2b)

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