Structure of PDB 1eef Chain H

Receptor sequence
>1eefH (length=103) Species: 562 (Escherichia coli) [Search protein sequence]
APQTITELCSEYRNTQIYTINDKILSYTESMAGKREMVIITFKSGETFQV
EVPGSQHIDSQKKAIERMKDTLRITYLTETKIDKLCVWNNKTPNSIAAIS
MKN
3D structure
PDB1eef Exploration of the GM1 receptor-binding site of heat-labile enterotoxin and cholera toxin by phenyl-ring-containing galactose derivatives.
ChainH
Resolution1.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GLA H E51 Q56 H57 Q61 W88 N90 K91 E51 Q56 H57 Q61 W88 N90 K91 PDBbind-CN: -logKd/Ki=2.92,IC50=1.2mM
BS02 I06 H Y12 I58 Y12 I58 PDBbind-CN: -logKd/Ki=2.92,IC50=1.2mM
Gene Ontology
Biological Process
GO:0031640 killing of cells of another organism
GO:0035821 modulation of process of another organism
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:1eef, PDBe:1eef, PDBj:1eef
PDBsum1eef
PubMed11173465
UniProtP32890|ELBP_ECOLX Heat-labile enterotoxin B chain (Gene Name=eltB)

[Back to BioLiP]