Structure of PDB 1dva Chain H

Receptor sequence
>1dvaH (length=254) Species: 9606 (Homo sapiens) [Search protein sequence]
IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWR
NLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPV
VLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNV
PRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHY
RGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLR
APFP
3D structure
PDB1dva Peptide exosite inhibitors of factor VIIa as anticoagulants.
ChainH
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.21: coagulation factor VIIa.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide H G38 V67 E70 L73 S74 H76 E80 S82 L144 L145 D146 L153 G22 V55 E58 L61 S62 H64 E68 S70 L135 L136 D137 L143
BS02 0Z6 H H57 G97 T98 T99 D189 S190 S195 S214 W215 G216 H41 G85 T86 T87 D186 S187 S192 S211 W212 G213
BS03 CA H E70 D72 E75 D77 E80 E58 D60 E63 D65 E68
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1dva, PDBe:1dva, PDBj:1dva
PDBsum1dva
PubMed10761907
UniProtP08709|FA7_HUMAN Coagulation factor VII (Gene Name=F7)

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