Structure of PDB 1cu4 Chain H

Receptor sequence

>1cu4H (length=215) Species: 10090 (Mus musculus) [Search protein sequence]

KLQQSGAELVRSGASVKLSCTASGFNIKDYYIQWVKQRPEQGLEWIGWID
PENGNSEYAPRFQGKATMTADTLSNTAYLQLSSLTSEDTAVYYCNADLHD
YWGQGTTLTVSSAKTTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVT
LTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPA
SSTKVDKKIEPRVTS

3D structure

PDB

1cu4 Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.

Chain

Resolution

2.9 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	H	D31 Y33 W50 D52 E53 E58 D95 L96	D29 Y31 W48 D50 E52 E57 D97 L98

External links

PDB	RCSB:1cu4, PDBe:1cu4, PDBj:1cu4
PDBsum	1cu4
PubMed	10543972

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