Structure of PDB 1aj7 Chain H

Receptor sequence
>1aj7H (length=217) Species: 9606 (Homo sapiens) [Search protein sequence]
QVQLQQSGAELVKPGASVKLSCTASGFNIKDTYMHWVKQRPEQGLEWIGR
IDPANGNTKYDPKFQGKATITADTSSNTAYLQLSSLTSEDTAVYYCASYY
GIYWGQGTTLTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEP
VTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVN
HKPSNTKVDKKVEPKSC
3D structure
PDB1aj7 Structural insights into the evolution of an antibody combining site.
ChainH
Resolution2.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NPE H Y33 H35 Y99 G100 W103 Y33 H35 Y100 G101 W104 MOAD: Kd=135uM
PDBbind-CN: -logKd/Ki=3.87,Kd=135uM
External links
PDB RCSB:1aj7, PDBe:1aj7, PDBj:1aj7
PDBsum1aj7
PubMed9180069
UniProtP01857|IGHG1_HUMAN Immunoglobulin heavy constant gamma 1 (Gene Name=IGHG1)

[Back to BioLiP]