Structure of PDB 7a01 Chain G5

Receptor sequence

>7a01G5 (length=137) Species: 9986 (Oryctolagus cuniculus)

PEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDLTKR
AGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANGLDN
KLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRR

3D structure

• PDB: 7a01 The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism.
• Chain: G5
• Resolution: 3.6 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	G5	R23 R24 K25 F28 G35 V36 G37 R38 R39 Y40 W82 F83 N85 R86 Q87 K88 H120 R121 R130 V131 R132 G133 Q134 H135 T136 K137 T138 G140 R142	R18 R19 K20 F23 G30 V31 G32 R33 R34 Y35 W77 F78 N80 R81 Q82 K83 H115 R116 R125 V126 R127 G128 Q129 H130 T131 K132 T133 G135 R137

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0015935 small ribosomal subunit
• GO:0022626 cytosolic ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7a01, PDBe:7a01, PDBj:7a01
• PDBsum: 7a01
• PubMed: 33296660
• UniProt: G1TPG3|RS18_RABIT Small ribosomal subunit protein uS13 (Gene Name=RPS18)