Structure of PDB 8y37 Chain G

Receptor sequence
>8y37G (length=175) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
SRVGKKIIDIPSDVTVTFDGNHVTVKGPKGELSRTLNERMTFKQEENTIE
VVRPSDSKEDRTNHGTTRALLNNMVQGVSQGYVKVLELVGVGYRAQMQGK
DLILNVGYSHPVEIKAEENITFSVEKNTVVKVEGISKEQVGALASNIRSV
RPPEPYKGKGIRYQGEYVRRKEGKT
3D structure
PDB8y37 Synthetic macrolides overcoming MLS B K-resistant pathogens.
ChainG
Resolution2.53 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna G S2 R3 V4 T63 G66 T67 L71 N74 K85 G108 Y109 S110 H111 K138 G142 Y157 K158 K160 K172 T176 S1 R2 V3 T62 G65 T66 L70 N73 K84 G107 Y108 S109 H110 K137 G141 Y156 K157 K159 K171 T175
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8y37, PDBe:8y37, PDBj:8y37
PDBsum8y37
PubMed38992047
UniProtQ7A084|RL6_STAAW Large ribosomal subunit protein uL6 (Gene Name=rplF)

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