Structure of PDB 8xfy Chain G

Receptor sequence
>8xfyG (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKAKVR
DRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLS
KEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLT
DFGLSKEFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQG
KDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEE
IKRHSFFSTIDWNKLYRREIHPPFKP
3D structure
PDB8xfy The Crystal Structure of RSK2 from Biortus.
ChainG
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1LU8 G Q76 F79 V82 K100 V131 F149 L150 L200 T210 D211 F212 Q18 F21 V24 K42 V71 F89 L90 L140 T150 D151 F152
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8xfy, PDBe:8xfy, PDBj:8xfy
PDBsum8xfy
PubMed
UniProtP51812|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 (Gene Name=RPS6KA3)

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