Structure of PDB 8w7c Chain G

Receptor sequence
>8w7cG (length=173) Species: 9606 (Homo sapiens) [Search protein sequence]
IPIVVDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHMY
INSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGMRH
SLPNSRIMIHQPSATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAM
ERDRYMSPMEAQEFGILDKVLVH
3D structure
PDB8w7c Activation of mitochondrial Caseinolytic Protease P (ClpP) induces selective cancer cell lethality
ChainG
Resolution3.0 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 R89 G L104 F105 S108 T135 Y138 L36 F37 S40 T67 Y70
BS02 R89 G R78 L79 E82 H116 Y118 W146 V148 R10 L11 E14 H48 Y50 W78 V80
External links
PDB RCSB:8w7c, PDBe:8w7c, PDBj:8w7c
PDBsum8w7c
PubMed
UniProtQ16740|CLPP_HUMAN ATP-dependent Clp protease proteolytic subunit, mitochondrial (Gene Name=CLPP)

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