Structure of PDB 8w2o Chain G

Receptor sequence
>8w2oG (length=232) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
SFDIWKNLDRIRSTKKNAGQFIKGSLLILPMRTEDKQQFDECMDELHKYI
SKDILRCYPQKMLFYIVLKDFNILDSCFVLSVLLAFQKRLWMAPSEKSYF
RVPKNINLTGSFYLPKNIETGSSIVEVGFNVVPDFQQFQVKACHVSKFMN
ELSNFFSQVEFGKCEANVINYFKREYNRTYSQISLALYELPLIGDGLFDI
KSYISKTRPIIETSKAQMIKHISEMKAYNEIS
3D structure
PDB8w2o Selected humanization of yeast U1 snRNP leads to global suppression of pre-mRNA splicing and mitochondrial dysfunction in the budding yeast.
ChainG
Resolution3.49 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna G N166 G225 K226 K236 N117 G162 K163 K173
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
Biological Process
GO:0000395 mRNA 5'-splice site recognition
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0000243 commitment complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005685 U1 snRNP
GO:0071004 U2-type prespliceosome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8w2o, PDBe:8w2o, PDBj:8w2o
PDBsum8w2o
PubMed38688558
UniProtQ03782|SNU56_YEAST 56 kDa U1 small nuclear ribonucleoprotein component (Gene Name=SNU56)

[Back to BioLiP]