Structure of PDB 8tof Chain G

Receptor sequence
>8tofG (length=369) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
EEEPKELLEKDSKGNIIKLNEPSTISEDSKVSVTGLPLNKGPSEKIKRES
LWNNRNDLKTFLTENMTEESNIRSTIGWNGDENEDFCSACNQSGSFLCCD
TCPKSFHFLCLDPPIDPNNLPKGDWHCNECKFKIFINNSMATLKKIESNF
IKQNNNVKIFAKLLFNIDSHNPKQFQLPNYIKETFPAVKTGSRGQYSDEN
DKIPLTDRQLFNTSYGQSITKLDSYNPDTHIDSNSGKFLICYKCNQTRLG
SWSHPENSRLIMTCDYCQTPWHLDCVPRASFKNLGSKWKCPLHSPTKVYK
KIVNYKVWKKQRLINKNQLYYEPLQKIGYQNNGNIQIIPDFKITQIDENS
IKYDFFDKIYKSKMVQKRK
3D structure
PDB8tof Structure of the complete Saccharomyces cerevisiae Rpd3S-nucleosome complex.
ChainG
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna G A317 K320 K321 A141 K144 K145
BS02 ZN G C263 C266 H283 C286 C87 C90 H107 C110
BS03 ZN G C417 C420 H448 C451 C241 C244 H272 C275
BS04 ZN G C440 C443 C466 H469 C264 C267 C290 H293
BS05 ZN G C275 C278 C303 C99 C102 C127
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006368 transcription elongation by RNA polymerase II
GO:0030174 regulation of DNA-templated DNA replication initiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0060195 negative regulation of antisense RNA transcription
Cellular Component
GO:0000118 histone deacetylase complex
GO:0005634 nucleus
GO:0032221 Rpd3S complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8tof, PDBe:8tof, PDBj:8tof
PDBsum8tof
PubMed38065958
UniProtQ04779|RCO1_YEAST Transcriptional regulatory protein RCO1 (Gene Name=RCO1)

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